{"id":6110,"date":"2026-03-23T10:33:23","date_gmt":"2026-03-23T10:33:23","guid":{"rendered":"https:\/\/www.turkof.at\/?post_type=turkof_service&p=6110"},"modified":"2026-05-20T06:33:32","modified_gmt":"2026-05-20T06:33:32","slug":"nanofat","status":"publish","type":"turkof_service","link":"https:\/\/www.turkof.at\/en\/services\/nanofat\/","title":{"rendered":"Nanofat"},"content":{"rendered":"\n
\n\t\n\t
\n\n\t\t\n\t\t
\n\t\t\t\"\"\n\n\t\t\t
\n\t\t\t\t\t\t\t\t\t
\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t4.9 stars on\t\t\t\t\t\t\tDocfinder<\/strong>\n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t

Nanofat<\/h1>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

Laser nanofat has already significantly shaped regenerative medicine\u2014and will continue to do so. Its effectiveness is well established, the mechanisms are suspected, but exactly how it works is still not fully understood.<\/p>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t

\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\tBook appointment\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\tBefore\/After images\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t
\n\t\t\t\t\"\"\n\n\t\t\t\t\t\t\t\t\t\"Nanofat\"\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\n\t<\/div>\n<\/div>\n\n\n\n
\n\t
\n\t\t\t\t\t
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t20+<\/strong>\n\t\t\t\t\tYears of experience\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\t\t
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t14<\/strong>\n\t\t\t\t\tVolumes of specialist literature\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\t\t
\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t920+<\/strong>\n\t\t\t\t\tSatisfied patients\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n\n\n
\n

Nanofat: what exactly is it, and why is it called that?<\/h2>\n\n\n\n

The term nanofat (English) or Nanofett (German) is, strictly speaking, a misleading label for fat-derived stem cells. The use of nanofat refers to the introduction of stem cells extracted from a person\u2019s own fat (known as \u201cadipose-derived stem cells\u201d) into the body.<\/p>\n\n\n\n

Thus, nanofat contains no intact fat cells, which means it is not a filler and cannot be used to correct volume deficits (e.g., under-eye circles, lips, nasolabial folds, etc.). Nanofat is therefore not a new form of fat grafting. Rather, it is a relatively new tool in aesthetic and regenerative medicine\u2014with vast potential and powerful future applications.<\/p>\n\n\n\n

The reason the term nanofat has become established in both medical literature and clinical language is because it was coined in the first publication on the topic in 2013 by two well-known plastic surgeons from Belgium, Patrick Tonnard and Alexis Verpaele.<\/p>\n\n\n\n

While the term is not entirely illogical, it remains somewhat confusing\u2014since no fat is actually used or implanted. The term derives from the method of processing the harvested fat. The fat, obtained via gentle liposuction, is mechanically emulsified\u2014repeatedly pushed back and forth through a very small metal opening. This breaks the fat down into fragments, essentially destroying nearly all fat cells until only a liquefied, emulsified form remains.<\/p>\n\n\n\n

As the fat cells are destroyed, the fragments become progressively smaller, which is why the authors adopted the term \u201cnano\u201d\u2014the final stage of miniaturization after macro, milli, and micro.<\/p>\n\n\n\n

Subsequently, a filtration system separates the destroyed fat from the remaining tissue. The result is a concentrated substance primarily composed of mesenchymal stem cells, which are small enough to pass through the filter. These are then used for the intended therapeutic purpose.<\/p>\n\n\n\n

In summary:<\/strong>
Nanofat contains no intact fat cells.
Nanofat equals fat-derived stem cells.
It offers a wide range of applications in regenerative and aesthetic medicine.<\/p>\n\n\n\n

\n
\n\n
\"Arzt <\/figure>\n\n<\/div>\n\n\n\n
\n\n

Mode of action of nanofat<\/h2>\n\n\n

The discovery that stem cells are present between fat cells\u2014that is, in the connective tissue of fat cells (known as the stromal vascular fraction)\u2014was made in 2001 by American researcher Patricia Zuk. In fatty tissue, especially subcutaneous fat, stem cells are found in relatively high concentrations (1\u201310%), compared to the much lower concentration in bone marrow (0.1\u20130.5%).<\/p>\n\n\n

The mode of action of nanofat is based on the ability of fat-derived stem cells to regenerate and repair tissue. Stem cells are precursor cells or progenitor cells that have the potential to differentiate into various cell types and to heal damaged tissue or replace destroyed cells.<\/p>\n\n\n

When stem cells are introduced into fat, they convert into fat cells; when introduced into another environment, they can adapt to the cell type of the recipient tissue (e.g., hair, muscle, nails, skin, etc.). This applies to many\u2014but not all\u2014cell types: they are pluripotent, but not omnipotent.<\/p>\n\n<\/div>\n<\/div>\n\n\n\n

Harvesting and production of nanofat<\/h2>\n\n\n\n

The first step in nanofat treatment is to extract a relatively small amount of fat tissue (usually 30\u201350\u202fml, maximum 100\u202fml) from the patient. This is typically done under local anesthesia using a special liposuction technique with particularly fine cannulas at a body site with sufficient subcutaneous fat, such as the abdomen or thighs.<\/p>\n\n\n\n

    \n
  1. The harvested fat tissue is mechanically processed to break down the fat cells and release the stem cells from the connective tissue matrix. This process usually involves pushing the fat through a filtration system that destroys the fat tissue but keeps the stem cells intact. This process is called emulsification or micronization.<\/li>\n\n\n\n
  2. Filtration:<\/span> After the fat cells have been destroyed, the liquid is pressed through one or two filters, leaving primarily the stem cells.<\/li>\n<\/ol>\n\n\n\n

    IMPORTANT:<\/strong> Until relatively recently, stem cells could only be produced in a certified and validated cleanroom laboratory. In such a lab, the fat cells were enzymatically dissolved in a process lasting several hours, and the stem cells were collected and concentrated. However, stem cells produced in the lab could not legally be reintroduced into the body without further approval due to medical regulations.
    Only since around 2010 have devices and instruments become available that allow stem cells to be separated from fat cells without using a lab\u2014this is done through mechanical destruction and filtration. This is the main reason why nanofat has only been used in regenerative and aesthetic medicine for about a decade (since 2011), and more widely only in the past five years, even though its existence has been known for over 20 years: thanks to the enormous simplification of the process in a closed system, practically any physician can now produce and apply nanofat in their own practice.<\/em><\/p>\n\n\n\n

    Depending on where the nanofat is to be injected, the resulting emulsion is transferred into syringes of various sizes, and\u2014depending on the area of application\u2014different sized needles or cannulas are attached to the syringe.
    For example, if nanofat is to be injected into a knee joint (for cartilage regeneration), a 10\u202fml syringe with a long, blunt cannula that doesn\u2019t need to be very fine is used.
    In contrast, for injecting stem cells into the scalp (for hair growth), only 1\u202fml syringes with very thin and short needles are needed.<\/p>\n\n\n\n

    \n
    \n\n

    Applications of nanofat \u2013 Overview<\/h2>\n\n\n

    Nanofat is used by numerous medical specialties for both regenerative and aesthetic purposes, with the aesthetic effect generally understood as a result of the regenerative properties of the stem cells.<\/p>\n\n\n